2017 Publications

Heubl, M., Zhang, J., Pressey, J. C., Al Awabdh, S., Renner, M., Gomez-Castro, F., … Lévi, S. (2017). GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl−-sensitive WNK1 kinase. Nature Communications, 8(1), 1776. http://doi.org/10.1038/s41467-017-01749-0
Furey, C. G., Timberlake, A. T., Nelson-Williams, C., Duran, D., Li, P., Jackson, E. M., & Kahle, K. T. (2017). Xp22.2 Chromosomal Duplication in Familial Intracranial Arachnoid Cyst. JAMA Neurology, 74(12), 1503. http://doi.org/10.1001/jamaneurol.2017.3399
Timberlake, A. T., Furey, C. G., Choi, J., Nelson-Williams, C., Loring, E., Galm, A., … Lifton, R. P. (2017). De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis. Proceedings of the National Academy of Sciences, 114(35), E7341–E7347. http://doi.org/10.1073/pnas.1709255114
Zhao, H., Nepomuceno, R., Gao, X., Foley, L. M., Wang, S., Begum, G., … Sun, D. (2017). Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke. Journal of Cerebral Blood Flow & Metabolism, 37(2), 550–563. http://doi.org/10.1177/0271678X16631561
Duran, D., Messina, R. D., Beslow, L. A., Montejo, J. D., Karimy, J. K., Gavankar Furey, C., … Kahle, K. T. (2017). Malignant Cerebellar Edema Subsequent to Accidental Prescription Opioid Intoxication in Children. Frontiers in Neurology, 8, 362. http://doi.org/10.3389/fneur.2017.00362
Karimy, J. K., Zhang, J., Kurland, D. B., Theriault, B. C., Duran, D., Stokum, J. A., … Kahle, K. T. (2017). Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus. Nature Medicine, 23(8), 997–1003. http://doi.org/10.1038/nm.4361
Zhang, J., Karimy, J. K., Delpire, E., & Kahle, K. T. (2017). Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport. Expert Opinion on Therapeutic Targets, 21(8), 795–804. http://doi.org/10.1080/14728222.2017.1351949
Vasquez, J. C., Huttner, A., Zhang, L., Marks, A., Chan, A., Baehring, J. M., … Dhodapkar, K. M. (2017). SOX2 immunity and tissue resident memory in children and young adults with glioma. Journal of Neuro-Oncology, 134(1), 41–53. http://doi.org/10.1007/s11060-017-2515-8
Glykys, J., Dzhala, V., Egawa, K., Kahle, K. T., Delpire, E., & Staley, K. (2017). Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential. Trends in Neurosciences, 40(5), 276–294. http://doi.org/10.1016/j.tins.2017.03.006
Gaillard, J., Klein, J., Duran, D., Storey, A., Scott, R. M., Kahle, K., & Smith, E. R. (2017). Incidence, clinical features, and treatment of familial moyamoya in pediatric patients: a single-institution series. Journal of Neurosurgery: Pediatrics, 19(5), 553–559. http://doi.org/10.3171/2016.12.PEDS16468
Shekarabi, M., Zhang, J., Khanna, A. R., Ellison, D. H., Delpire, E., & Kahle, K. T. (2017). WNK Kinase Signaling in Ion Homeostasis and Human Disease. Cell Metabolism, 25(2), 285–299. http://doi.org/10.1016/j.cmet.2017.01.007
Duran, D., Hadzipasic, M., & Kahle, K. T. (2017). Mystery Case: Acute hydrocephalus caused by radiographically occult fourth ventricular outlet obstruction. Neurology, 88(5), e36–e37. http://doi.org/10.1212/WNL.0000000000003555
Delpire, E., & Kahle, K. T. (2017). The KCC3 cotransporter as a therapeutic target for peripheral neuropathy. Expert Opinion on Therapeutic Targets, 21(2), 113–116. http://doi.org/10.1080/14728222.2017.1275569
Grunwald, Z., Beslow, L. A., Urday, S., Vashkevich, A., Ayres, A., Greenberg, S. M., … Sheth, K. N. (2017). Perihematomal Edema Expansion Rates and Patient Outcomes in Deep and Lobar Intracerebral Hemorrhage. Neurocritical Care, 26(2), 205–212. http://doi.org/10.1007/s12028-016-0321-3
Bhuiyan, M. I. H., Song, S., Yuan, H., Begum, G., Kofler, J., Kahle, K. T., … Sun, D. (2017). WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats. Journal of Cerebral Blood Flow & Metabolism, 37(8), 2780–2794. http://doi.org/10.1177/0271678X16675368