
Principal Investigator
Kristopher T. Kahle, M.D., Ph.D.
Pediatric Neurosurgeon | Neurosurgeon | Geneticist
- Director, Pediatric Neurosurgery, Massachusetts General Hospital
- Director, Harvard Center for Hydrocephalus and Neurodevelopmental Disorders (HAND)
- Member, Yale-NIH Centers for Mendelian Genomics
Dr. Kahle is the Director of Pediatric Neurosurgery at the Massachusetts General Hospital (MGH) and the Harvard Center for Hydrocephalus and Neurodevelopmental Disorders (HAND). He is a board-certified pediatric neurosurgeon, with experience in a broad range of pediatric neurosurgical disorders including brain and spinal cord tumors and cysts, all types of hydrocephalus, Chiari malformation, spina bifida, vascular malformations, and others. He also treats these conditions in transitional age patients and adults, providing continuity of care across the age spectrum. He is highly skilled in both open and endoscopic/minimally invasive neurosurgical techniques.
Dr. Kahle is a fellow of the American Association of Neurological Surgeons (AANS) and a member of numerous medical organizations, including the AANS, Congress of Neurological Surgeons (CNS), American Society of Pediatric Neurosurgeons (ASPN), and the International Society of Pediatric Neurosurgeons (ISPN).
Dr. Kahle graduated cum laude from the University of Chicago in 1999 with degrees in Biology and Philosophy. He received his M.D. from Yale School of Medicine in 2007, where he also received his Ph.D. working in the laboratory of human geneticist Richard Lifton. He completed his neurosurgery residency training at MGH in 2014, as well as a post-doctoral research fellowship at Harvard University with co-mentors Stephen Elledge and David Clapham. He completed a clinical pediatric neurosurgery fellowship at Boston Children’s Hospital, where he was Shellito staff associate and Instructor of Neurosurgery at Harvard Medical School. Dr. Kahle returned to New Haven to join the Yale School of Medicine faculty, where he was Assistant Professor of Neurosurgery, Pediatrics, and Cellular & Molecular Physiology, and Director of Neonatal and Congenital Anomaly Neurosurgery from 2016-2021. In 2021, Dr. Kahle came to Massachusetts General Hospital to serve as Director of Pediatric Neurosurgery. He is also Nicholas T. Zervas Associate Professor of Neurosurgery at Harvard Medical School, Associate Member of Broad Institute of MIT and Harvard, and Investigator for the Division of Genetics and Genomics at Boston Children's Hospital.

Garrett Allington
PhD Candidate
Yale University

Carla Fortes
Senior Research Associate, Kahle Lab
Massachusetts General Hospital

Emre Kiziltug
MD Candidate
Yale School of Medicine

Kedous Mekbib
MD/MHS Candidate
Yale School of Medicine

Susan P. Mullany, NP
Nurse Practitioner
Massachusetts General Hospital

Duy Phan
MD/PhD Candidate
Yale School of Medicine

Stephanie Robert, MD, PhD
Resident Physician, Department of Neurosurgery
Postdoctoral Fellow, Kahle Lab
Yale New Haven Hospital

Hannah Smith, BS
Clinical Research Coordinator, Kahle Lab
Massachusetts General Hospital

Julie Choi
PhD Candidate
Washington University School of Medicine

Po-Ying Fu
Bioinformatics Research Analyst
Washington University in St. Louis

Adam Kundishora, MD
Chief Neurosurgery Resident
Yale New Haven Hospital

Andres Moreno De Luca, MD
Associate Neuroradiologist, Department of Radiology
Assistant Professor, Autism & Developmental Medicine Institute and Genomic Medicine Institute

Carol Nelson-Williams
Senior Research Scientist
Yale University

Paulina Piwowarczyk
Research Associate
Boston Children's Hospital

Myron Rolle, MD, MSc
Neurosurgery Resident
Massachusetts General Hospital

Yung-Chun (David) Wang
Postdoctoral Fellow
Washington University School of Medicine

Tyrone Despenza Jr.
MD/PhD Candidate
Yale School of Medicine

Kristin Hanifin, MSN, APRN, CPNP
Nurse Practitioner
Massachusetts General Hospital

Arnaud Marlier, PhD
Senior Research Scientist

Quentin Moyer
MD Candidate
Harvard Medical School

Jack Ocken
Undergraduate Research Associate
Yale College

Benjamin Reeves
MD/PhD Candidate
Yale School of Medicine

JP Shohfi
Clinical Research Coordinator
Massachusetts General Hospital

Max Wrubel
Research Student
McDonnell Genome Institute

Shujuan Zhao
PhD Candidate
Washington University School of Medicine
Lab Alumni

August Allocco
MD Candidate
Yale School of Medicine

Weilai Dong
PhD Candidate
Yale University

Sierra Conine
Postgraduate Associate in Neurosurgery
Yale University

Ashley Dunbar, MD
Neurosurgery Resident
Washington University School of Medicine

Eyiyemisi Damisah, MD
Assistant Professor of Neurosurgery
Yale University

Daniel Duran, MD
Neurosurgery Resident
University of Mississippi Medical Center

Charuta Furey, MD
Neurosurgery Resident
Barrow Neurological Institute

Jason Karimy
MD Candidate
Quinnipac School of Medicine
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Amrita Singh
MD Candidate
Yale School of Medicine

Jonathan Gaillard, MD
HHMI Medical Research Fellow

Shreyas Panchagnula, MD, MHS
Resident, University of Maryland Medical Center Neurosurgery Department

Will Sullivan
Yale College

Ava Hunt
MD Student
Rutgers School of Medicine

Amar Sheth
MD Candidate
Yale School of Medicine

Xue Zeng
PhD Candidate, Yale University
Graduate Assistant, Rockefeller University
